Category: News

4 Natural Ways to Boost Mood


Mood disorders have become epidemic. Over 40 million Americans are taking prescription drugs for depression or anxiety. Natural ways to stabilize mood and achieve mental health can often be just as beneficial as pharmaceutical agents, without causing bothersome side effects. Let’s take a closer look at four simple and effective approaches.

  1. Dichromatic green light therapy – Green light has been successful in treating Seasonal Affective Disorder (SAD), and is effective at regulating circadian rhythms. It is thought to affect brain chemicals associated with mood, as well as reset the body’s internal clock. Green light therapy has also had a positive effect on non-seasonal depression, sleep disorders, and other conditions.
  2. Warm Shower Followed by Cold Shower – Hydrotherapy (applying water to the skin) has been used since ancient times as a method of balancing the body and mind. Exposure to cold water is thought to stimulate the release of norepinephrine in the brain and increase blood levels of both beta-endorphin and norepinephrine – which directly and indirectly improve mood.  Warm water helps relieve stress and muscle tension. Alternating cold with warm water helps strengthen the circulatory system as well as the sympathetic/parasympathetic nervous system, and helps remove toxins from the body. Starting your day with a cold/warm shower will get your blood pumping, your feel-good hormones flowing, and your body and mind invigorated.
  3. Salt and soda baths – Combine a half-cup of Epsom salts with a half-cup of baking soda in hot bath water and soak for 20 minutes. Since Epsom salts are another name for magnesium sulfate, this bath will not only remove toxins from your body, but it will also help to boost magnesium levels, which in turn helps to boost serotonin levels in the brain, improving mood. (Magnesium is necessary to convert tryptophan to serotonin.)
  4. Amino acids: Glycine, Methionine and Magnesium aspartate – Amino acids are the building blocks of proteins in the body, and have historically been obtained from the diet. However, as highly processed, fatty foods and chemical food additives have become staples of the American diet, unstable mental and emotional health have become all too common. For optimum psychological health, the body must eliminate chemicals and toxins. Nutrient deficits reduce the body’s capacity for detoxification. Toxins and chemicals that are not properly cleared become free to interfere with the body’s own chemicals and chemical messengers, particularly neurotransmitters, which affect mood and thought patterns.

          – L-methionine is key to maintaining clear detoxification pathways in the liver and brain. In the liver, the L-methionine acts to chelate heavy metals, much-documented contributors to mental and emotional disorders. Researchers are increasingly discovering the importance of methionine in the treatment of depression. In a random, double-blind, placebo-controlled trial, oral supplementation of S-adenosylmethionine significantly improved symptoms of major depression. In another study of patients with major depression, researchers found an inverse relationship between plasma levels of S-adenosylmethionine and symptoms of depression.*Glycine, used by the brain as a control neurotransmitter, regulates sleep rhythms, thereby producing calmness and aiding sleep. It also sustains the phase II detoxification pathway in the liver, neutralizing and clearing toxins.*

          – Magnesium, which is implicated in nerve irritability and mood instability, is required for nerve transmission, and maintaining normal mood levels.* Magnesium aspartate has been shown in various research studies to be an important nutrient for correcting mood swings, nerve irritability, and help with depression.*

For natural support of mood and emotional health, PERQUE Mood Guard, delivers a synergetic combination of nutrients that are necessary for mental and emotional stability. Healthcare practitioners, click here to request professional samples. To find an Authorized Distributor of PERQUE Mood Guard, contact PERQUE Client Services at 1.800.525.7372.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

7 integrative sleep recommendations to achieve better overall state of health


It’s no secret that most Americans could use an extra amount of sleep every night. In fact, nearly 8-in-10 Americans admit they would feel better and more prepared for the day if they had an extra hour of sleep. More than a third of Americans aren’t getting the required amount of sleep per night. Healthy restorative sleep plays a critical role in immune function, metabolism, memory, learning, and other vital functions. The following tips on how to sleep better can make it easier to get through the day and achieve a better overall state of health.

Here are 7 integrative sleep recommendations from Health Studies Collegium:

1) Incorporate relaxing rituals like salt & soda baths with calming essential oils. Other modalities include abdominal breathing, active meditation to link relaxation response with  breath and dichromatic green light for 20 minutes prior to bed to improve Galvanic Skin Response (GSR) and help remove toxins. Enhancing magnesium, which is a calming and relaxing mineral,  is extremely helpful as well.

2) Keep devices out of the bedroom. Many people look at their phones, computers or tablets right before attempting to fall asleep. This isn’t a good idea. It’s important to stay away from devices in the bedroom. Some find value in turning off routers and other sources of electromagnetic fields.

3) Sleep in a room as dark as possible. Many people enjoy falling asleep while the television is on. This is not a good idea to receive the best night’s sleep. It’s important to maintain a room that is dark.

4) Consider enhanced uptake tryptophan with B6 and zinc to enrich serotonin and melatonin where they are helpful yet staying within physiology. Take 30 minutes before retiring for the night. We do not recommend systemically flooding the body with active neurochemicals that nature restricts in location and duration. We recommend physiology before pharmacology. See PERQUE Sleep Guard.

5) Do not eat within three hours of retiring for the night. Eat foods that can be digested, assimilated and eliminated without immune burden. Use LRA tests to determine delayed allergy burdens that can interfere with restorative sleep rhythms.

6) Avoid caffeinated drinks after lunch and stay hydrated with water and alkalinizing beverages instead.

7) As you fall asleep, see yourself receiving inspiration, insight and guidance during the restorative sleep ahead.

Get the lead out safely and naturally

Dr. Russell Jaffe recently posted about how you can get the lead out of your system, safely and naturally, on PERQUE. Here is the article:

Lead is a heavy, toxic mineral. After decades of documenting how harmful lead can be even in tiny amounts, there is renewed interest in what to do to avoid such increasingly common risks. There is much you can do to reduce lead uptake and enhance safer lead removal from the body. The Health Studies Collegium Foundation recommends the following 21st Century lead risk and harm reduction plan:

Ascorbates based on C Cleanse determined amount – Always 100% l-ascorbate, fully buffered and reduced

High sulfur foods as diet staples ± supplementation – ‘Make staples out of condiments and condiments out of staples’

Enhance magnesium uptake and chaperone its delivery to cells – Combine ionized magnesium with special choline citrate

Selenomethionine as a helpful and detoxifying form of selenium – Nature’s safer, preferred form of selenium

Healthier cells have enough essential antioxidant and buffering nutrients to keep a reserve of energy in the form of magnesium ATP, the currency of cell biology. Healthy cells have an ATP to ADP ratio of 100:1 or more. This means efficient transduction of electrons from membrane through cytoplasm and chaperoned through the mitochondrial cell battery without free radical electrons inducing oxidative damage.

Ascorbates protect and recycle all other antioxidants

Ascorbate can safely chaperone toxic minerals such as lead from the body when taken based on individual C Cleanse. Ascorbate wraps around minerals like lead and escorts them into the urine, stool and sweat. Health Studies Collegium estimates that each gram of ascorbate is able to help remove about 10 micrograms of toxic minerals from the body. Given the toxic mineral load of most people, several grams of ascorbate are needed just to address the daily traffic or flux of dietary and environmental (xenobiotic) sources of lead and similar minerals. Since toxic minerals cause antioxidants to be used up, larger amounts of ascorbates are needed by individuals with larger body burdens of toxic minerals, especially those toxic minerals actively in traffic within the circulation and metabolically active tissues of the body.

Sulfur and magnesium help protect from toxic minerals

In addition, healthy people make a molecular sponge known as metallothionein (MT) to soak up and safely chaperone lead (and other toxic minerals) from the body. MT is a distinct polypeptide made up of the simplest amino acid (glycine) and a sulfur containing amino acid (cysteine). In addition, zinc and magnesium bind to the peptide. MT is found in every fluid and every part of the body as long as people are in healthier elective protective mode at the cell level.

In order for the body to produce MT, there must be ample sulfur sources in the diet and the cell must be energetic enough to produce elective protective molecules such as MT. Garlic, Ginger, Onions, Broccoli sprouts and Eggs, known by the acronym GGOBE, are good sources of sulfur in the diet. We recommend these five high sulfur foods be staples of the diet rather than condiments.

In addition to MT, there are other sulfur containing molecules that can be sacrificed so that toxic metals like lead do not wreak havoc on delicate cell centers and systems. These include glutathione, cysteine, and methionine. These sulfur-containing molecules bind lead and other toxic minerals making them more water soluble and less toxic. Sulfur-containing molecules can become depleted when they bind lead and other toxic minerals to prevent them from being free and more harmful. From drinking water to seafood; from air to water, food and medicines, it is impossible to avoid toxic minerals such as lead.

How much is too much

Physicians, in the 1970s, were taught that treatment was indicated for levels of lead in the blood above 50 micrograms (µgm). The threshold for treatment has been progressively lowered several times over the decades and now is at 5 µgm in the blood, based on World Health Organization and Center for Disease Control recommendations. Reduced intelligence, mood and impulse control problems and increased risk of chronic illness are all linked to increased body burden of lead and similar toxic minerals.

Since exposure to toxic minerals such as lead, mercury, cadmium, arsenic and nickel today is from 100 to 10,000 times higher than it was just a century or two ago, it seems prudent to increase the safer antitoxins such as sulfur sources in the diet, ascorbates and other compounds such as selenomethionine that can bind irreversibly and render less toxic lead and other toxic minerals while helping remove them through urine, stool and sweat.

Mechanism of action

As is true for essentially all toxic substances, it is the lack of protective antioxidants and/or buffering minerals that allows the adverse oxidative free radical burst… the allostatic and homeostatic load to occur.

Magnesium also plays an important role in toxic mineral uptake and harm. When magnesium is sufficient, uptake of toxic minerals from the intestine is largely blocked. When magnesium is insufficient, uptake of toxic minerals is enhanced.

When magnesium is sufficient, B vitamins work better and cell proton gradients allow for mitochondrial batteries to delivery both ATP and acid protons to cell cytoplasm in exchange for electrons that shuttle through ascorbate, glutathione, and nucleotides as the sources for the ATP energy.

When magnesium is insufficient, risk of oxidative harm and free radical damage for toxic metals such as lead are greater. Cell metabolic acidosis means loss of the proton gradient essential to energy production. In practice, this means that people in the lower half of the usual range for serum magnesium have chronic latent magnesium deficiency (CLMD). CLMD increases lead’s adverse effects.
CLMD also increases risk of viral or other infectious agent finding a hospitable niche in people lacking the reserves to remove toxic minerals.

D-penicillamine when needed

Ascorbates, sulfur sources, magnesium and selenomethionine form a team to protect and defend from toxic minerals. Sometimes, additional therapy is needed. D-penicillamine (d-pen) is dimethylcysteine, a more water-soluble sulfur containing aminoacid. D-pen is also a divalent cation chelator; it wraps around and chaperones any mineral with two charges. This is the basis for the d-pen provocation test. The d-pen is taken for three (3) days and a 24 hour urine collected on the second day. This specimen can be analyzed both for essential, nutritional minerals and for toxic minerals. We suggest ICP-MS as the most reliable analytic tool.

Advantages of d-pen over other chelators include it being oral, water soluble, and easily able to go across all barriers without re-depositing toxins at the blood brain barrier, the loop of Henle nor the choroid plexus. D-pen is made by bacterial fermentation. No longer made form penicillin, d-pen shows little if any cross reactivity in people who are penicillin allergic. When needed, patch tests can confirm that people do or do not have delayed reactions to d-pen. Other chelators are more selective and less effective than d-pen. Examples include EDTA, EGTA, DTPA, DMSA and DMPS.

Now more than ever there is need to get the lead out more safely and effectively. Be proactive and confirm that you are getting enough of the essential nutrients to protect from toxic mineral harm despite the toxic environment in which we live.

PERQUE Can help get the lead out… Safely & Naturally

PERQUE Potent C Guard                      Based on C Cleanse

PERQUE Mag Plus Guard                    Base on 1st urine pH after rest

PERQUE Choline Citrate                      Enhance magnesium uptake & chaperone to cells

PERQUE Life Guard tabsules              40 actives including selenomethionine

PERQUE Detox IN Guard tabsules     Sulfur sources + lead-out nutrients

Click here to read about PERQUE Life Guard.

To get started with PERQUE, call 1.800.525.7372 or send us an email to

Not getting enough sleep? You’re not alone

Stress, family issues, problems at home, medical issues—getting the recommended amount of sleep can be a difficult task even for the best of sleepers. In fact, according to a recent study done by the Centers for Disease Control and Prevention (CDC) Morbidity and Mortality Weekly Report, more than a third of Americans are not getting enough sleep on a regular basis. You’re not alone by any means.

The American Academy of Sleep Medicine and the Sleep Research Society recommend that adults 18 to 60 get at least seven hours of sleep each night in order to promote ideal health and well-being. Thirty five percent of Americans are sleeping fewer than the recommended amount of hours, resulting in higher rates of obesity, diabetes, high blood pressure, heart disease, stroke and mental distress.

“As a nation, we are not getting enough sleep,” said Wayne Giles, M.D., director of CDC’s Division of Population Health.

Results of the study varied by geography, race, ethnicity, employment and marital status. The research included data from the 2014 Behavioral Risk Factor Surveillance System which is a state-based, random digit-dialed telephone survey conducted by state health departments and CDC.

Here are some of the important findings from the study:

– Healthy sleep duration was lower among Native Hawaiians/Pacific Islanders (54 percent), non-Hispanic blacks (54 percent), multiracial non-Hispanics (54 percent) and American Indians/Alaska Natives (60 percent) compared with non-Hispanic whites (67 percent), Hispanics (66 percent), and Asians (63 percent).

– The prevalence of healthy sleep duration varied among states and ranged from 56 percent in Hawaii to 72 percent in South Dakota.

– A lower proportion of adults reported getting at least seven hours of sleep per day in states clustered in the southeastern region of the United States and the Appalachian Mountains. Previous studies have shown that these regions also have the highest prevalence of obesity and other chronic conditions.

– People who reported they were unable to work or were unemployed had lower healthy sleep duration (51 percent and 60 percent, respectively) than did employed respondents (65 percent). The prevalence of healthy sleep duration was highest among people with a college degree or higher (72 percent).

– The percentage reporting a healthy sleep duration was higher among people who were married (67 percent) compared with those who were never married (62 percent) or divorced, widowed, or separated (56 percent).

Are you part of the millions upon millions of Americans who suffer from a lack of sleep? PERQUE Sleep Guard is your answer to a healthy and improved quality of sleep and quality of life.

PERQUE Sleep Guard enhances restful, healing sleep by restoring healthy brain chemistry. A safer and natural alternative to habit-forming pharmaceuticals, PERQUE Sleep Guard boosts the body’s own production of serotonin, allowing the brain to operate properly, resulting in better brain activity, mood and energy.

Call PERQUE at 1.800.525.7372 to find a PERQUE Authorized Distributor. Healthcare professionals, call to order your PERQUE Sleep Guard today!


What is GGOBE and why is it important?

Super-foods like garlic, ginger, onions broccoli sprouts and eggs (GGOBE) support healthy detoxification systems by providing the body a very special mineral — sulfur, according to Dr. Russell Jaffe. One of the most abundant in the body, sulfur is required for the synthesis of glutathione, one of our premier endogenous antioxidants, taurine that helps with the cardiovascular system and other amino acids like methionine and cysteine that aid in comprehensive detoxification.

GGOBE, especially the vegetables, also provide a nutrient called sulforaphane, an organosulfur compound. Sulforaphane exhibits anticancer, antidiabetic, and antimicrobial properties. These super bio-detox foods are also a rich source of IP-6 which aids in the metabolism of insulin and calcium, promotes healthy hair growth, bone marrow cell metabolism, eye membrane development and helps the liver transfer fat to other parts of the body. We suggest regularly incorporating these foods daily to add variety to the diet and to achieve that jump-start in functional detoxification.

Do you have an egg intolerance? If so, read this informative post from Better Lab Tests Now on egg intolerance


Milk Thistle – Not Just for Detox

Milk ThistleWith the holidays, parties, and eating splurges behind us, there is no better time than now to detoxify the body and shed some extra pounds. Your patients/clients, whether they tell you or not, are likely thinking about starting their 2016 detox. And they will have lots of company. There are many detox recommendations out there ranging from helpful to just plain silly, and even dangerous. You can help your patients sort through the information and detox safely by offering them guidance and an effective protocol to use.

One key agent to include in any detoxification protocol is Silymarin (or milk thistle). Silymarin is well known for its liver support and cleansing properties, and there is research showing it can help decrease blood sugar levels in those with diabetes. It has also been shown to improve insulin resistance – a precursor to diabetes and a huge trigger factor for weight gain. Read more.

Since regular detoxification not only removes unwanted toxins and helps with weight loss, but also strengthens the immune system, increases energy and improves skin quality, now really is a great time to detox!

Detoxification is one of five key elements of the clinically validated Well Guard training. In this presentation by Dr. Russell Jaffe you'll hear strategies for getting the bad stuff out and the good stuff in. You'll also learn about PERQUE Liva Guard Forte containing silymarin and the complete PERQUE Detox Program that provides comprehensive nutrients for a complete multi-system detoxification.


Travel Tips for Sustained Wellness

DrJaffeTravelTipsMEMEDr. Jaffe was recently asked how he maintains his health-promoting routines given his heavy travel schedule. Here are Dr. Jaffe's recommendations for staying well while you travel.

Travel Tip From “Road Warrior, Dr. Russell Jaffe

  1. Plan a travel day because delays and diversions occur so often now that it makes sense to provide flexible time. When schedules work, there might be time to see an exhibit or catch a show. When on planes, drink 8 ounces of water per hour of flight. Chair hatha / prana yoga and active meditation help balance out the flight.
  2. Know where you are staying, find a green grocer or Whole Foods type market so that you can stock your room with whole foods — those we can digest, assimilate and eliminate without immune burden. Stay out of restaurants to the extent possible. Find organic / raw food / whole food local restaurants when ‘en suite’ eating is not feasible.
  3. Line up supplements next to the array of colorful foods.
  4. Carry stretching bands to help with stretching — before bed and on waking while in bed, in the shower, in the hot tub and / or somewhere for a total of 20 minutes along with a 20-45 minute amble… in the greenest place nearby.
  5. Noise canceling headphones and eye shades are helpful when you want to cocoon.
  6. Schedule a Feldenkrais / Trager / Alexander technique session when possible. Seek out word of mouth referrals to people with healing hands.
  7. Use the basics of the health club from sauna to hot tub when available. Avoid spa or hotel massages because there are a lot of inexperienced body workers.
  8. Use travel as a challenge to our usual habits… bring a beginner’s mind, a sense of ourselves as beings of light within larger spheres of light and gratitude for meaningful work.



Autism Summit Online

Autism spectrum disorders are the fastest growing developmental disorder in the world today.

In the United States a child is diagnosed every 11 minutes. For the past three decades the rates have increased at an accelerating rate and are currently 1in 68 children; 1 in 48 boys and 1 in 189 girls are affected.

This is the first online Autism Summit. The compilation of experts across multiple disciplines with cutting edge and innovative therapies make this summit unique, with a comprehensive, inclusive, credible approach to a much-debated issue.

Learn from video interviews with Functional Medicine visionaries and innovators that are experts in root cause resolution.

Autism spectrum disorders are a complex chronic condition with a large variation in symptoms. The cause remains elusive. A series of scientific studies over the last decade document that the increase is a real and cannot be attributed to better diagnosis.

There is a need to think deeply and objectively about this disorder. We know that multiple body systems are impacted, including: brain, nervous, immune, gastrointestinal, oxidation/reduction, inflammation, and mitochondria

We have assembled an outstanding group of doctors, parents, clinicians, chiropractors, nutritionists, and researchers that can shed light on this complex chronic condition. Our experts discuss the environmental connection and share with you cutting edge information about what you can do to improve the health and well being of your child.

Learn the latest, most up to date information about autism spectrum disorders, including ADHD. Discover how early intervention and treatment, and life-long support can make a difference for individuals with autism and their families

The real answers are likely not being offered by mainstream medicine. We have traveled the country to interview 35 respected and trustworthy practitioners. It can often seem like there’s no options and no one else to turn to, The Autism Intensive Summit will help you get to the root of dysfunction in you child by giving you information you need to address:

  • Diet, nutrition, supplements, neutraceuticals, pharmaceutical, and essential oils
  • Healing the leaky gut
  • How to detoxify/eliminate heavy metals and environmental pollutants in food, air and water.
  • Treating chronic infections
  • Hear from parents how they have been able to make dramatic positive changes in their children
  • Understand biochemical and physiological basis for efficacy of biomedical interventions
  • How to begin a comprehensive approach
  • Body oriented therapies

There are many reasons why we seeing an alarming increase in autism spectrum disorder, by sharing this information we can do something about it! Collectively we know enough to prevent and remediate autism spectrum disorders.

Measure Mineral Status & Metabolic Acidosis Risk

The pH level of urine after 6 hours of rest reflects pH throughout the body. Levels below 6.5 indicate metabolic acidosis. Low pH also suggests mineral deficits, because minerals are pulled from bone and body fluid during metabolic acidosis to buffer and reduce acids and maintain pH within a health range.

Acid-alkaline balance is important. Tiny changes in pH have profound implications for cell metabolism. Life exists poised exquisitely just above the neutral point of 7.0. Levels of pH above 7.5 can indicate catabolic illness in which amino acids are used as energy sources.

Any unusual variation in urinary pH is usually reflected in the first morning urine. This calls for changes in diet and/or nutritional supplements to restore acid-alkaline balance. Simply checking the pH level each day provides ongoing monitoring to see whether pH has been corrected. (Click here for 1st AM Urine pH test protocol) This is an important aspect of biochemistry – so if there is an abnormality, that has to be monitored regularly.

Healthy values are urine pH in the 6.5-7.5 range.

Measure your 1st AM Urine pH with the 15-day self-test kit available from ELISA/ACT Biotechnologies. Call 1.800.553.5472 to order yours.

Get Prepared for Cold & Flu Season

In a recent episode of Five to Thrive Live, Dr. Lise Alschuler and Karolyn Gazella talk to Russell Jaffe, MD, Ph.D.,CCN about  cold and flu prevention strategies.  Hear Dr. Jaffe's insights on natural and effective methods of enhancing immunity and overall health. Dr. Jaffe also discusses his opinion on the flu vaccine and his personal cold and flu prevention protocol. Whether you are a practitioner preparing to treat cold and flu or an individual looking to boost your defenses, you'll want to listen to this interview. 

For more information about any of Dr. Jaffe's recommendations, contact PERQUE Integrative Health at 1.800.525.7372 or by email at You can also submit a question directly.


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