Tag: GI Immunity

Gut Hyperpermeability

The gut is a major, potential portal of entry into the body for foreign antigens. Only its intact mucosal barrier protects the body from foreign antigen entry and systemic exposure.

This mucosal barrier is made up of non-immunological components (mucous coat, mucous membranes) working independently and in concert with the local mucosal immune system (secretory IgA, lymphoid elements in Peyer’s patches). Its effective functioning is peripherally assisted by a competent immune system (especially IgA production, RES function), specific hepatobiliary functions (Kupffer cell activation/phagocytosis, hepatocyte function, bile production and elimination), a healthy/balanced population of host-friendly microflora (roughly a 20-40/60-80 ratio of Gram negative to Gram positive with sufficient percent of Lactobacillus species), and optimal digestive processes (adequate HCI/pepsin and pancreatic digestive enzyme activity, optimal soluble fiber intake, low transit time). 

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Ask Dr. J: Corn sensitivity and animals who have ingested corn feeds

On this edition of “Ask Dr. J”, Dr. Jaffe is asked if we should avoid animals who have ingested corn-based feeds …

Dr. Russell Jaffe discusses collagen

On this edition of “Ask Dr. J”, Dr. Russell Jaffe talks about how collagen is formed and repaired in the body …

Why do people suffer from heart attacks due to ischemia but we don’t hear about nose or ear attacks?

Why do people suffer from heart attacks due to ischemia but we don’t hear about nose or ear attacks? Dr. Russell Jaffe …