Tag: GI Immunity

Gut Hyperpermeability

The gut is a major, potential portal of entry into the body for foreign antigens. Only its intact mucosal barrier protects the body from foreign antigen entry and systemic exposure.

This mucosal barrier is made up of non-immunological components (mucous coat, mucous membranes) working independently and in concert with the local mucosal immune system (secretory IgA, lymphoid elements in Peyer’s patches). Its effective functioning is peripherally assisted by a competent immune system (especially IgA production, RES function), specific hepatobiliary functions (Kupffer cell activation/phagocytosis, hepatocyte function, bile production and elimination), a healthy/balanced population of host-friendly microflora (roughly a 20-40/60-80 ratio of Gram negative to Gram positive with sufficient percent of Lactobacillus species), and optimal digestive processes (adequate HCI/pepsin and pancreatic digestive enzyme activity, optimal soluble fiber intake, low transit time). 

Read more

How long after receiving LRA test results should you start to detox?

On this episode of “Ask Dr. J”, Dr. Russell Jaffe is asked how long after receiving LRA test results should you …

Are immediate allergies permanent?

On this episode of “Ask Dr. J”, Dr. Russell Jaffe is asked if immediate allergies are permanent, or if they can …

Dr. Russell Jaffe on arsenic in rice and age group concerns

On this episode of “Ask Dr. J”, Dr. Russell Jaffe is asked if we should be concerned about arsenic in our rice, …