Tag: leaky gut

Gut Hyperpermeability

The gut is a major, potential portal of entry into the body for foreign antigens. Only its intact mucosal barrier protects the body from foreign antigen entry and systemic exposure.

This mucosal barrier is made up of non-immunological components (mucous coat, mucous membranes) working independently and in concert with the local mucosal immune system (secretory IgA, lymphoid elements in Peyer’s patches). Its effective functioning is peripherally assisted by a competent immune system (especially IgA production, RES function), specific hepatobiliary functions (Kupffer cell activation/phagocytosis, hepatocyte function, bile production and elimination), a healthy/balanced population of host-friendly microflora (roughly a 20-40/60-80 ratio of Gram negative to Gram positive with sufficient percent of Lactobacillus species), and optimal digestive processes (adequate HCI/pepsin and pancreatic digestive enzyme activity, optimal soluble fiber intake, low transit time). 

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Ask Dr. J: Can Nitric Oxide be effectively used as a supplement?

In this week’s edition of “Ask Dr. J”, Dr. Russell Jaffe is asked whether or not Nitric Oxide can be effectively …

Dr. Russell Jaffe on common causes of vertigo and strategies to help resolve it

In this week’s edition of “Ask Dr. J”, Dr. Russell Jaffe is asked about the common causes of vertigo and …

Dr. Russell Jaffe on whether it’s possible to test for delayed sensitivities using hair

In this week’s edition of “Ask Dr. J”, Dr. Russell Jaffe is asked if it’s possible to test for delayed …