In this edition of “Ask Dr. J”, Dr. Russell Jaffe talks about peak plasma concentrations of Vitamin C through therapeutic dosing.
Tag: Vitamin C
In this week’s “Ask Dr. J”, Dr. Russell Jaffe is asked if the plasma level of Vitamin C reflects the needs of other tissues in the body.
In this edition of “Ask Dr. J”, Dr. Jaffe talks about the difference between Ascorbic Acid and buffered Vitamin C.
In this week’s “Ask Dr. J”, Dr. Russell Jaffe is asked if the Dynamic Flow Model of Vitamin C is still valid.
In this week’s edition of “Ask Dr. J”, Dr. Russell Jaffe is asked what the actual problem could be if someone experiences lower back pain and cloudy urine while on Vitamin C.
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In this week’s “Ask Dr. J”, Dr. Russell Jaffe is asked how does Vitamin C treat infection, decrease oxidative stress, increase phagocytic activity, increase collagen resistance and direct antiviral activity.
In this week’s “Ask Dr. J”, Dr. Russell Jaffe is asked if Vitamin C should be taken with Quercetin Dihydrate in order to allow for regenerating Vitamin C in the body.
I always refer to Vitamin C (ascorbate) as the mother of all antioxidants; it heals, repairs and detoxifies the body of extraneous elements among numerous other uses. Since we all have different physiological needs, I usually recommend intakes based on the C-Cleanse Protocol rather than just what is required to prevent scurvy. (https://www.holisticprimarycare.net/topics/topics-o-z/prevention-practice-pearls/1558-inflammation-revealed-tamed-and-resolved.html ). This C-Cleanse Protocol that I developed allows for personalized dosing for each individual. I encourage using only fully buffered, fully reduced and recrystallized 100% l-ascorbate; other forms of the vitamin being irritating or unhelpful either due to being synthetic or due to being oxidized in processing and storage.
So, it makes me cringe when I see vitamin C being held in a negative light and especially in connection with kidney stones – a fairly recurrent story at that. Various critics and medical authors through the years have labeled taking large doses of vitamin C “dangerous” because it is thought to produce kidney stones. This was the first argument that critics attacked Linus Pauling with years ago when he wrote his book “Vitamin C and the Common Cold”. The idea seems to stem from the fact that oxalate stone is the most common type (75%) of kidney stone and because a significant percentage of ascorbate is metabolized into and excreted as oxalic acid, it is surmised that this oxalic acid combines with calcium in the urine and deposits as calcium oxalate kidney stones.
The practice of cautioning people against using vitamin C because it produces kidney stones continues even today unfortunately (http://www.renalandurologynews.com/kidney-stones/kidney-stone-risk-in-men-linked-to-vitamin-c-intake/article/448096/) even though facts and studies indicate otherwise(Curhan GC, Willett WC, Speizer FE, Stampfer MJ. Intake of vitamins B6 and C and the risk of kidney stones in women. J Am Soc Nephrol. 1999 Apr;10(4):840-5 and Auer BL, Auer D, Rodgers AL. The effect of ascorbic acid ingestion on the biochemical and physicochemical risk factors associated with calcium oxalate kidney stone formation. Clin Chem Lab Med. 1998 Mar;36(3):143-7).
Then what is the real story?
Although ascorbate does increase the production of oxalate in the body, it really does not increase stone formation per se. In fact it works quite the other way. Ascorbate tends to bind with calcium leaving less calcium to bind with oxalate and in effect prevents the formation of calcium oxalate stone.
Another important point – kidney stone formation is largely connected with infection. Extra-tiny microorganisms that live in the urine can, by precipitating calcium and other minerals around themselves, induce the formation of kidney stones. Large doses of ascorbate are bactericidal and strive to prevent stone formation by removing the bacteria around which stones form.
Ascorbate can also prevent other types of kidney stones. Less common forms of stone for example include uric acid stones (8%), that form in gout, and cystine stones (1%), which can occasionally be formed in children with a hereditary condition and these stones are not side effects of vitamin C.
- Adequate hydration — 8 glasses of 8 ounces of water a day keeps the urine dilute enough that kidney stones cannot form.
- Adding calibrated ascorbate intake – following the C-Cleanse Protocol further protects the kidneys and bladder from toxins, reduces stone formation risk, and sustains healthy kidney health.
On this edition of “Ask Dr. J”, Dr. Russell Jaffe is asked to explain the development of acquired immunity through …